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CJC-1295 (Mod GRF 1-29) amplifies GH pulse amplitude via the GHRH receptor, Ipamorelin initiates clean GH pulses via ghrelin receptor without elevating cortisol or prolactin, and MK-677 (Ibutamoren) provides sustained 24-hour GH elevation and robust IGF-1 increase through oral ghrelin mimetic activity with a ~24-hour half-life

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